Lavendustin B

Lavendustin B inhibits HIV-1 integrase (IN) interaction with its cognate cellular cofactor lens epithelium-derived growth factor (LEDGF/p75). Lavendustin B is an inhibitor of Tyrosine Kinase and also a competitive inhibitor of glucose transporter 1 (Glut1).

Product information

CAS Number: 125697-91-8

Molecular Weight: 365.38

Formula: C21H19NO5

Chemical Name: 5-[Bis[(2-hydroxyphenyl)methyl]amino]-2-hydroxy-benzoic Acid

Smiles: OC(=O)C1=CC(=CC=C1O)N(CC1=CC=CC=C1O)CC1=CC=CC=C1O

InChiKey: RTYOLBQXFXYMKY-UHFFFAOYSA-N

InChi: InChI=1S/C21H19NO5/c23-18-7-3-1-5-14(18)12-22(13-15-6-2-4-8-19(15)24)16-9-10-20(25)17(11-16)21(26)27/h1-11,23-25H,12-13H2,(H,26,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 73 mg/mL (199.79 mM) Ethanol 73 mg/mL (199.79 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Fatima E Agharbaoui, et al. Eur J Med Chem. 2016 Nov 10;123:673-683.
2. J C Vera, et al. Biochemistry. 2001 Jan 23;40(3):777-90.

Products are for research use only. Not for human use.