详情描述
DGY-06-116 is an irreversible covalent and selective inhibitor of Src with IC50 of 2.6 nM.
Product information
CAS Number: 2556836-50-9
Molecular Weight: 597.11
Formula: C32H33ClN8O2
Chemical Name: 4-((2-acrylamidophenyl)amino)-N-(2-chloro-6-methylphenyl)-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidine-5-carboxamide
Smiles: CN1CCN(CC1)C1C=CC(=CC=1)NC1=NC(NC2=CC=CC=C2NC(=O)C=C)=C(C=N1)C(=O)NC1=C(Cl)C=CC=C1C
InChiKey: HLRQYOGLZWIOPA-UHFFFAOYSA-N
InChi: InChI=1S/C32H33ClN8O2/c1-4-28(42)36-26-10-5-6-11-27(26)37-30-24(31(43)38-29-21(2)8-7-9-25(29)33)20-34-32(39-30)35-22-12-14-23(15-13-22)41-18-16-40(3)17-19-41/h4-15,20H,1,16-19H2,2-3H3,(H,36,42)(H,38,43)(H2,34,35,37,39)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.