详情描述
GSK2643943A is an inhibitor of deubiquitylating enzyme (DUB) with IC50 of 160 nM for USP20/Ub-Rho.
Product information
CAS Number: 2449301-27-1
Molecular Weight: 277.30
Formula: C17H12FN3
Synonym:
GSK-2643943A
GSK 2643943A
Chemical Name: (E)-2-amino-6-(3-fluorostyryl)-1H-indole-3-carbonitrile
Smiles: NC1NC2=CC(/C=C/C3=CC(F)=CC=C3)=CC=C2C=1C#N
InChiKey: CGXBPMZRTMXEIA-SNAWJCMRSA-N
InChi: InChI=1S/C17H12FN3/c18-13-3-1-2-11(8-13)4-5-12-6-7-14-15(10-19)17(20)21-16(14)9-12/h1-9,21H,20H2/b5-4+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO 55 mg/mL (198.34 mM) Ethanol 8 mg/mL (28.85 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Mark Kemp. Prog Med Chem. 2016;55:149-92.
Products are for research use only. Not for human use.