详情描述
cis-22a is a TRPV6 inhibitor (IC50 = 0.32 μM), which exhibits selectivity against related TRPV channels and calcium channels. cis-22a displays antiproliferative effects on T47D human breast cancer cells.
Product information
CAS Number: 1819366-84-1
Molecular Weight: 563.53
Formula: C26H31F6N3O4
Synonym:
cis22a
cis 22a
Chemical Name: 1-(pyridin-3-yl)-4-((1s,4s)-4-(m-tolyl)cyclohexyl)piperazine bis(2,2,2-trifluoroacetate)
Smiles: CC1=CC(=CC=C1)[C@@H]1CC[C@@H](CC1)N1CCN(CC1)C1=CN=CC=C1.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F
InChiKey: UMKPISXYUQWXJJ-XWOHEVPJSA-N
InChi: InChI=1S/C22H29N3.2C2HF3O2/c1-18-4-2-5-20(16-18)19-7-9-21(10-8-19)24-12-14-25(15-13-24)22-6-3-11-23-17-22;2*3-2(4,5)1(6)7/h2-6,11,16-17,19,21H,7-10,12-15H2,1H3;2*(H,6,7)/t19-,21+;;
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.