详情描述
High affinity and selective σ1 receptor antagonist (pKi values are 10.28-10.85, 5.81-6.53 and 5.80 at σ1, σ2 and DAT). Displays σ1/σ2 selectivity ratio of 29512. Selectively blocks binge eating without a general inhibition of food intake in rats.
Product information
CAS Number: 1204401-49-9
Molecular Weight: 337.48
Formula: C21H23NOS
Synonym:
WQ1
WQ-1
TC WQ 1
TCWQ 1
TC-WQ 1
TC WQ1
TC WQ-1
TCWQ1
TC-WQ-1
TC Sigma1
TC-Sigma1
TC Sigma-1
TC Sigma 1
Chemical Name: 2-(1-benzylpiperidin-4-yl)thiochroman-4-one
Smiles: O=C1CC(SC2=CC=CC=C21)C1CCN(CC2C=CC=CC=2)CC1
InChiKey: XWMHOCDNGHEUMF-UHFFFAOYSA-N
InChi: InChI=1S/C21H23NOS/c23-19-14-21(24-20-9-5-4-8-18(19)20)17-10-12-22(13-11-17)15-16-6-2-1-3-7-16/h1-9,17,21H,10-15H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.