Pleuromutilin

Pleuromutilin (Drosophilin B, Mutilin 14-glycolate), the lead compound for novel antibiotics, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.

Product information

CAS Number: 125-65-5

Molecular Weight: 378.50

Formula: C22H34O5

Synonym:

A 4014C

A-4014C

A4014C

NSC 121145

Drosopholin B

Pleuromulin

Chemical Name: Acetic acid, hydroxy-, 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester, (3aS-(3aalpha,4beta,5alpha,6alpha,8beta,9alpha,9abeta,10S*))- (9CI)

Smiles: C[C@@]12[C@@H]3C(=O)CC[C@]3(CC[C@H]1C)[C@@H](C)[C@H](O)[C@@](C)(C[C@H]2OC(=O)CO)C=C

InChiKey: ZRZNJUXESFHSIO-FEOSZSLTSA-N

InChi: InChI=1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21-,22-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 76 mg/mL(200.79 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Y-Z Tang, et al. Mini Rev Med Chem. 2012 Jan;12(1):53-61.

Products are for research use only. Not for human use.