Indole-3-carbinol

Indole-3-carbinol (I3C) inhibits NF-κB activity and also is an Aryl hydrocarbon receptor (AhR) agonist, and an inhibitor of WWP1 (WW domain-containing ubiquitin E3 ligase 1).

Product information

CAS Number: 700-06-1

Molecular Weight: 147.17

Formula: C9H9NO

Synonym:

I3C

3-Indolemethanol

Chemical Name: (1H-indol-3-yl)methanol

Smiles: OCC1=CNC2=CC=CC=C21

InChiKey: IVYPNXXAYMYVSP-UHFFFAOYSA-N

InChi: InChI=1S/C9H9NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-5,10-11H,6H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 29 mg/mL(197.03 mM). Water: 7 mg/mL(47.56 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Majid Safa, et al. Tumour Biol . 2015 May;36(5):3919-30.

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