详情描述
D-64131 is a potent and selective tubulin inhibitor. D-64131 inhibits tumor cell proliferation in vitro (IC50 = 74 nM). In xenograft experiments with the human amelanoic melanoma MEXF 989, D-64131 was highly active with treatment resulting in a growth delay of 23.4 days at 400 mg/kg.
Product information
CAS Number: 74588-78-6
Molecular Weight: 251.28
Formula: C16H13NO2
Chemical Name: 2-benzoyl-5-methoxy-1H-indole
Smiles: COC1C=C2C=C(NC2=CC=1)C(=O)C1C=CC=CC=1
InChiKey: ICMIJSRDISNKOC-UHFFFAOYSA-N
InChi: InChI=1S/C16H13NO2/c1-19-13-7-8-14-12(9-13)10-15(17-14)16(18)11-5-3-2-4-6-11/h2-10,17H,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.