详情描述
BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.
Product information
CAS Number: 943962-47-8
Molecular Weight: 424.30
Formula: C19H15Cl2NO4S
Chemical Name: 3,5-dichloro-2-hydroxy-N-{4-methoxy-[1,1'-biphenyl]-3-yl}benzene-1-sulfonamide
Smiles: COC1=CC=C(C=C1NS(=O)(=O)C1=CC(Cl)=CC(Cl)=C1O)C1C=CC=CC=1
InChiKey: SIIPNDKXZOTLEA-UHFFFAOYSA-N
InChi: InChI=1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.