(S)-Dolaphenine Hydrochloride

(S)-Dolaphenine hydrochloride is a component of Dolastatin 10 (HY-15580). Dolastatin 10, an antineoplastic agent, inhibits tubulin polymerization.

Product information

CAS Number: 135383-60-7

Molecular Weight: 240.75

Formula: C11H13ClN2S

Chemical Name: (1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethan-1-amine hydrochloride

Smiles: Cl.N[C@@H](CC1C=CC=CC=1)C1=NC=CS1

InChiKey: XQCUEKANDANWHG-PPHPATTJSA-N

InChi: InChI=1S/C11H12N2S.ClH/c12-10(11-13-6-7-14-11)8-9-4-2-1-3-5-9;/h1-7,10H,8,12H2;1H/t10-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 50 mg/mL (207.68 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Zhou W , et al. A practical approach to asymmetric synthesis of dolastatin 10. Org Biomol Chem. 2017;15(29):6119-6131.

Products are for research use only. Not for human use.