Cevimeline hydrochloride hemihydrate(cis)

Cevimeline (AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.

Product information

CAS Number: 1462862-74-3

Molecular Weight: 244.78

Formula: C20H38Cl2N2O3S2

Synonym:

Evoxac

Chemical Name: bis((2R, 5'S)-5'-methyl-4-azaspiro[bicyclo[2.2.2]octane-2, 2'-[1, 4]oxathiolane]) hydrate dihydrochloride

Smiles: O.Cl.Cl.C[C@@H]1O[C@@]2(CN3CCC2CC3)CS1.C[C@@H]1O[C@@]2(CN3CCC2CC3)CS1 |&1:4,6,17,19|

InChiKey: ZSTLCHCDLIUXJE-PRMDKKRTSA-N

InChi: InChI=1S/2C10H17NOS.2ClH.H2O/c2*1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11;;;/h2*8-9H,2-7H2,1H3;2*1H;1H2/t2*8-,10+;;;/m11.../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Barbe AG. Medication-Induced Xerostomia and Hyposalivation in the Elderly: Culprits, Complications, and Management. Drugs Aging. 2018 Oct;35(10):877-885.

Products are for research use only. Not for human use.