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详情描述

β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity.

Product information

CAS Number: 14901-07-6

Molecular Weight: 192.30

Formula: C13H20O

Chemical Name: (3E)-4-(2, 6, 6-trimethylcyclohex-1-en-1-yl)but-3-en-2-one

Smiles: CC1CCCC(C)(C)C=1/C=C/C(C)=O

InChiKey: PSQYTAPXSHCGMF-BQYQJAHWSA-N

InChi: InChI=1S/C13H20O/c1-10-6-5-9-13(3,4)12(10)8-7-11(2)14/h7-8H,5-6,9H2,1-4H3/b8-7+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

β-Ionone is an analog of β-carotenoids which widely distributed in fruit and vegetables. β-ionone (25, 50, 100 and 200 μM; for 24 and 48 h) inhibits SGC-7901 cell line growth. The measured IC50 value is 89 μM.

References:

  1. Mahsa Ansari, et al. β-Ionone and Its Analogs as Promising Anticancer Agents. Eur J Med Chem. 2016 Nov 10;123:141-154.

Products are for research use only. Not for human use.

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