详情描述
Cambendazole is one of the most effective agents for the therapy of human strongyloidiasis.
Product information
CAS Number: 26097-80-3
Molecular Weight: 302.35
Formula: C14H14N4O2S
Synonym:
Novazole
Noviben
Equiben
Cambendazole
Chemical Name: isopropyl (2-(thiazol-4-yl)-1H-benzo[d]imidazol-5-yl)carbamate
Smiles: CC(C)OC(=O)NC1C=C2N=C(NC2=CC=1)C1=CSC=N1
InChiKey: QZWHWHNCPFEXLL-UHFFFAOYSA-N
InChi: InChI=1S/C14H14N4O2S/c1-8(2)20-14(19)16-9-3-4-10-11(5-9)18-13(17-10)12-6-21-7-15-12/h3-8H,1-2H3,(H,16,19)(H,17,18)
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
References:
- Andrade SR, Scarminio IS, Nery MM, de Oliveira AC. Comparison of multivariate calibration methods to determine simultaneously mebendazole-cambendazole and mebendazole-thiabendazole in pharmaceutical preparations by UV-visible spectrophotometry. J Pharm Biomed Anal. 2003 Nov 24;33(4):655-65. PubMed PMID: 14623591.
- Lyons ET, Drudge JH, Tolliver SC, Swerczek TW, Stamper S, Granstrom DE. Control of cambendazole-resistant small strongyles (Population S) with oxibendazole in a pony band: an 8 year field test (1984-1992). Vet Parasitol. 1994 Apr;52(3-4):271-7. PubMed PMID: 8073610.
- Sharma RK, Singh K, Saxena KK. Effect of cambendazole and haloxon on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae (Nematoda). Angew Parasitol. 1990 May;31(2):101-5. PubMed PMID: 2389827.
- Grove DI, Northern C. The effects of thiabendazole, mebendazole and cambendazole in normal and immunosuppressed dogs infected with a human strain of Strongyloides stercoralis. Trans R Soc Trop Med Hyg. 1988;82(1):146-9. PubMed PMID: 3176142.
Products are for research use only. Not for human use.