详情描述
5-Hydroxymethyldeoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM).
Product information
CAS Number: 5116-24-5
Molecular Weight: 258.23
Formula: C10H14N2O6
Synonym:
Hydroxymethyldeoxyuridine
α-Hydroxythymidine
2'-Deoxy-5-(hydroxymethyl)uridine
Chemical Name: Uridine, 2'-deoxy-5-(hydroxymethyl)
Smiles: O[C@@H]1C[C@H](O[C@H]1CO)N1C=C(CO)C(=O)NC1=O
InChiKey: IPAVKOYJGUMINP-CSMHCCOUSA-N
InChi: InChI=1S/C10H14N2O6/c13-3-5-2-12(10(17)11-9(5)16)8-1-6(15)7(4-14)18-8/h2,6-8,13-15H,1,3-4H2,(H,11,16,17)/t6-,7+,8+/m1/s1
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
Products are for research use only. Not for human use.