详情描述
Pomalidomide 4-PEG4-acid is a functionalized cereblon ligand for PROTAC® research and development. It incorporates an E3 ligase ligand plus a PEG4 linker with terminal carboxylic acid ready for conjugation to a target protein ligand It is part of a range of functionalized tool molecules for PROTAC R&D.
Product information
CAS Number: 2138440-81-8
Molecular Weight: 521.52
Formula: C24H31N3O10
Synonym:
Pomalidomide 4PEG4acid
Pomalidomide
Pomalidomide 4-PEG4-acid
Pomalidomide 4-PEG4
Chemical Name: 1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oic acid
Smiles: OC(=O)CCOCCOCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
InChiKey: CAANPUBZFFRWQP-UHFFFAOYSA-N
InChi: InChI=1S/C24H31N3O10/c28-19-5-4-18(22(31)26-19)27-23(32)16-2-1-3-17(21(16)24(27)33)25-7-9-35-11-13-37-15-14-36-12-10-34-8-6-20(29)30/h1-3,18,25H,4-15H2,(H,29,30)(H,26,28,31)
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
Products are for research use only. Not for human use.