Thalidomide 4-ether-alkylC8-acid

Thalidomide 4-ether-alkylC8-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry.

Product information

CAS Number: 2225148-51-4

Molecular Weight: 430.45

Formula: C22H26N2O7

Synonym:

Thalidomide 4ether alkylC8 acid

Thalidomide 4-ether-alkylC8-acid

Thalidomide 4ether alkylC8

Thalidomide 4etheralkylC8acid

Chemical Name: 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)nonanoic acid

Smiles: OC(=O)CCCCCCCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChiKey: JDVPWEYIVOQCDX-UHFFFAOYSA-N

InChi: InChI=1S/C22H26N2O7/c25-17-12-11-15(20(28)23-17)24-21(29)14-8-7-9-16(19(14)22(24)30)31-13-6-4-2-1-3-5-10-18(26)27/h7-9,15H,1-6,10-13H2,(H,26,27)(H,23,25,28)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.

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