详情描述
Pomalidomide 4-PEG2-acid is a cereblon ligand with PEG linker and terminal acid for onward chemistry. It is a unctionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG2 linker with terminal acid ready for conjugation to a target protein ligand. It is part of a range of functionalized tool molecules for PROTAC R&D.
Product information
CAS Number: 2140807-17-4
Molecular Weight: 433.41
Formula: C20H23N3O8
Synonym:
Pomalidomide 4PEG2acid
Pomalidomide 4PEG2
Pomalidomide 4-PEG2-acid
Chemical Name: 3-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)propanoic acid
Smiles: OC(=O)CCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
InChiKey: NKISJPXMSOQWER-UHFFFAOYSA-N
InChi: InChI=1S/C20H23N3O8/c24-15-5-4-14(18(27)22-15)23-19(28)12-2-1-3-13(17(12)20(23)29)21-7-9-31-11-10-30-8-6-16(25)26/h1-3,14,21H,4-11H2,(H,25,26)(H,22,24,27)
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
Products are for research use only. Not for human use.