详情描述
Pomalidomide 4-alkylC8-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry. It is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. It is part of a range of functionalized tool molecules for PROTAC R&D.
Product information
CAS Number: 2305936-70-1
Molecular Weight: 429.47
Formula: C22H27N3O6
Synonym:
Pomalidomide4-alkylC8acid
Pomalidomide4-alkylC8
Pomalidomide 4-alkylC8-acid
Chemical Name: 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid
Smiles: OC(=O)CCCCCCCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
InChiKey: OGMJVYCYINHWEJ-UHFFFAOYSA-N
InChi: InChI=1S/C22H27N3O6/c26-17-12-11-16(20(29)24-17)25-21(30)14-8-7-9-15(19(14)22(25)31)23-13-6-4-2-1-3-5-10-18(27)28/h7-9,16,23H,1-6,10-13H2,(H,27,28)(H,24,26,29)
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
Products are for research use only. Not for human use.