Pomalidomide 4-PEG1-acid

Pomalidomide 4-PEG1-acid is a cereblon ligand with PEG linker and terminal acid for onward chemistry.

Product information

CAS Number: 2139348-60-8

Molecular Weight: 389.36

Formula: C18H19N3O7

Synonym:

Pomalidomide4-PEG1acid

Pomalidomide 4PEG1

Pomalidomide 4-PEG1-acid

Pomalidomide4PEG1acid

Chemical Name: 3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid

Smiles: OC(=O)CCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChiKey: GXCGXOBFROXMLV-UHFFFAOYSA-N

InChi: InChI=1S/C18H19N3O7/c22-13-5-4-12(16(25)20-13)21-17(26)10-2-1-3-11(15(10)18(21)27)19-7-9-28-8-6-14(23)24/h1-3,12,19H,4-9H2,(H,23,24)(H,20,22,25)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Qiu X, et al. Jiang B. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019;21(10):3838-3841.

Products are for research use only. Not for human use.