Pomalidomide 4-alkylC7-acid

Pomalidomide 4-alkylC7-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry.

Product information

CAS Number: 2225940-51-0

Molecular Weight: 415.44

Formula: C21H25N3O6

Synonym:

Pomalidomide4alkylC7acid

Pomalidomide4-alkylC7

Pomalidomide 4-alkylC7-acid

Chemical Name: 8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octanoic acid

Smiles: OC(=O)CCCCCCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChiKey: IJDAOSIFULSGHH-UHFFFAOYSA-N

InChi: InChI=1S/C21H25N3O6/c25-16-11-10-15(19(28)23-16)24-20(29)13-7-6-8-14(18(13)21(24)30)22-12-5-3-1-2-4-9-17(26)27/h6-8,15,22H,1-5,9-12H2,(H,26,27)(H,23,25,28)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Zhang X, et, al. Discovery of PROTAC BCL-X L degraders as potent anticancer agents with low on-target platelet toxicity. Eur J Med Chem. 2020 Apr 15; 192: 112186.

Products are for research use only. Not for human use.