ACY-775

ACY-775 is a potent and selective histone deacetylase 6 (HDAC6) inhibitor with IC50 of 7.5  nM.

Product information

CAS Number: 1375466-18-4

Molecular Weight: 330.36

Formula: C17H19FN4O2

Chemical Name: 2-((1-(3-Fluorophenyl)cyclohexyl)amino)-N-hydroxypyrimidine-5-carboxamide

Smiles: ONC(=O)C1C=NC(NC2(CCCCC2)C2=CC=CC(F)=C2)=NC=1

InChiKey: IYBURCQQEUNLDL-UHFFFAOYSA-N

InChi: InChI=1S/C17H19FN4O2/c18-14-6-4-5-13(9-14)17(7-2-1-3-8-17)21-16-19-10-12(11-20-16)15(23)22-24/h4-6,9-11,24H,1-3,7-8H2,(H,22,23)(H,19,20,21)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 66 mg/mL(199.78 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Jeanine Jochems, et al. Neuropsychopharmacology. 2014 Jan;39(2):389-400.

Products are for research use only. Not for human use.