Ampalex (CX-516)

Ampalex (CX-516, Ampakine CX 516, BDP-12, SPD 420) is a positive allosteric modulator of AMPA receptor. Ampalex exhibits potential treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).

Product information

CAS Number: 154235-83-3

Molecular Weight: 241.29

Formula: C14H15N3O

Synonym:

CX 516

CX516

BDP 12

BDP-12

BDP12

SPD-420

SPD420

Chemical Name: 1-(quinoxalin-6-ylcarbonyl)piperidine

Smiles: O=C(C1=CC2=NC=CN=C2C=C1)N1CCCCC1

InChiKey: ANDGGVOPIJEHOF-UHFFFAOYSA-N

InChi: InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 48 mg/mL (198.93 mM) Water 48 mg/mL (198.93 mM) Ethanol 48 mg/mL (198.93 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Christian Krintel, et al. Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1645-52.
2. Wojciech Danysz. Curr Opin Investig Drugs. 2002 Jul;3(7):10

Products are for research use only. Not for human use.