3-Aminotyrosine

3-Aminotyrosine is a Tyrosine derivative, being a useful probe to study the role of redox active tyrosines in enzymes. Unnatural amino acid that induces red shift when incorporated into fluorescent proteins and fluorescent protein-based biosensors. Causes spontaneous and efficient red shift of GFP in HEK293T cells, shifting excitation and emission maxima by 56 and 95 nm respectively. Induces red shift in a range of fluorescent proteins containing tyrosine-derived chromophores, including teal fluorescent mTFP1, yellow fluorescent Citrine, and circularly permuted YFP and GFP. Also induces red-shift in fluorescent protein-based biosensors, including iGluSnFR (a glutamate sensor), iGABASnFR (a GABA sensor), dLight1.2 (a dopamine sensor) and iATPSnFR1.1 (an ATP sensor).

Product information

CAS Number: 23279-22-3

Molecular Weight: 269.13

Formula: C9H14Cl2N2O3

Synonym:

3-Aminotyrosine dihydrochloride

3 Aminotyrosine dihydrochloride

Chemical Name: (S)-2-amino-3-(3-amino-4-hydroxyphenyl)propanoic acid dihydrochloride

Smiles: Cl.Cl.NC1=CC(C[C@H](N)C(O)=O)=CC=C1O

InChiKey: PIFWBMTWCTUOOQ-KLXURFKVSA-N

InChi: InChI=1S/C9H12N2O3.2ClH/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14;;/h1-3,7,12H,4,10-11H2,(H,13,14);2*1H/t7-;;/m0../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.