详情描述
Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba. Bilobalide is important for producing several of the effects of Gingko biloba extracts. It has neuroprotective effects, as well as effects inducing the liver enzymes CYP3A1 and 1A2, which may be partially responsible for interactions between gingko and other herbal medicines or pharmaceutical drugs. Bilobalide has recently been found to be a negative allosteric modulator at the GABAA and GABAA-rho receptors. Of GABAA, it may possibly be selective for the subunits predominantly implicated in cognitive and memory functioning such as α1.
Product information
CAS Number: 33570-04-6
Molecular Weight: 326.30
Formula: C15H18O8
Synonym:
(-)-Bilobalide
Chemical Name: (1S,4R,7R,8S,9R,11S)-9-tert-butyl-7,9-dihydroxy-3,5,12-trioxatetracyclo[6.6.0.0¹,¹¹.0⁴,⁸]tetradecane-2,6,13-trione
Smiles: CC(C)(C)[C@]1(O)C[C@@H]2OC(=O)C[C@]32C(=O)O[C@@H]2OC(=O)[C@H](O)[C@@]312
InChiKey: MOLPUWBMSBJXER-YDGSQGCISA-N
InChi: InChI=1S/C15H18O8/c1-12(2,3)14(20)4-6-13(5-7(16)21-6)10(19)23-11-15(13,14)8(17)9(18)22-11/h6,8,11,17,20H,4-5H2,1-3H3/t6-,8-,11-,13-,14+,15+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.