详情描述
Clotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch. Clotrimazole works to kill individual Candida or fungal cells by altering the permeability of the fungal cell wall. It binds to phospholipids in the cell membrane and inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production. This leads to the cell's death via loss of intracellular elements. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system.
Product information
CAS Number: 23593-75-1
Molecular Weight: 344.84
Formula: C22H17ClN2
Synonym:
CLT
Canesten
Lotrimin
Chemical Name: 1-[(2-chlorophenyl)diphenylmethyl]-1H-imidazole
Smiles: ClC1=CC=CC=C1C(C1C=CC=CC=1)(C1C=CC=CC=1)N1C=NC=C1
InChiKey: VNFPBHJOKIVQEB-UHFFFAOYSA-N
InChi: InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.