详情描述
5(6)-TAMRA contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.
Product information
CAS Number: 98181-63-6
Molecular Weight: 430.45
Formula: C50H44N4O10
Synonym:
5(6)-Carboxytetramethylrhodamine
Chemical Name: 9-(4( or 5)-carboxy-2-carboxylatophenyl)-3, 6-bis(dimethylamino)-10-xanthen-10-ylium
Smiles: CN(C)C1=CC2=[O+]C3=CC(=CC=C3C(C3=CC=C(C=C3C([O-])=O)C(O)=O)=C2C=C1)N(C)C.CN(C)C1=CC2=[O+]C3=CC(=CC=C3C(C3=CC(=CC=C3C([O-])=O)C(O)=O)=C2C=C1)N(C)C
InChiKey: PYOXZPUMKLJOGA-UHFFFAOYSA-N
InChi: InChI=1S/2C25H22N2O5/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31;1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)17-8-5-14(24(28)29)11-20(17)25(30)31/h2*5-13H,1-4H3,(H-,28,29,30,31)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 125 mg/mL (290.39 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Fuchs SM, et al. Pathway for polyarginine entry into mammalian cells. Biochemistry. 2004 Mar 9;43(9):2438-44.
- Gerber D, et al. Insertion and organization within membranes of the delta-endotoxin pore-forming domain, helix 4-loop-helix 5, and inhibition of its activity by a mutant helix 4 peptide. J Biol Chem. 2000 Aug 4;275(31):23602-7.
- Vinayak R, et al. Automated, solid-phase coupling of rhodamine dye acids to 5' amino oligonucleotides. Nucleic Acids Symp Ser. 2000;(44):257-8.
Products are for research use only. Not for human use.