详情描述
Acipimox, also known as Olbemox and K-9321, is hormone-sensitive lipase inhibitor. Acipimox treatment resulted in a robust elevation in expression of nuclear-encoded mitochondrial gene sets and a mitonuclear protein imbalance, which may indicate activation of the mitochondrial unfolded protein response. Further studies in C2C12 myotubes confirmed a direct effect of acipimox on NAD(+) levels, mitonuclear protein imbalance, and mitochondrial oxidative capacity.
Product information
CAS Number: 51037-30-0
Molecular Weight: 154.12
Formula: C6H6N2O3
Chemical Name: 6-methyl-1-oxo-1λ⁵-pyrazine-3-carboxylic acid
Smiles: CC1=CN=C(C=N1=O)C(O)=O
InChiKey: DJQOOSBJCLSSEY-UHFFFAOYSA-N
InChi: InChI=1S/C6H6N2O3/c1-4-2-7-5(6(9)10)3-8(4)11/h2-3H,1H3,(H,9,10)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.