详情描述
Adarotene, also known as ST1926, is an atypical retinoid and a promising anti-tumour agent with selective apoptotic activity on the leukaemic blast. The anti-tumour activity of the compound has been associated with its capacity to induce DNA double stranded breaks. (source: Eur J Cancer. 2012 Dec 11. pii: S0959-8049(12)00909-4.).
Product information
CAS Number: 496868-77-0
Molecular Weight: 374.47
Formula: C25H26O3
Chemical Name: (2E)-3-[3'-(adamantan-1-yl)-4'-hydroxy-[1,1'-biphenyl]-4-yl]prop-2-enoic acid
Smiles: OC1=CC=C(C=C1C12CC3CC(C1)CC(C2)C3)C1C=CC(/C=C/C(O)=O)=CC=1
InChiKey: QAWBIEIZDDIEMW-FPYGCLRLSA-N
InChi: InChI=1S/C25H26O3/c26-23-7-6-21(20-4-1-16(2-5-20)3-8-24(27)28)12-22(23)25-13-17-9-18(14-25)11-19(10-17)15-25/h1-8,12,17-19,26H,9-11,13-15H2,(H,27,28)/b8-3+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.