详情描述
ADL5859 is a potent, orally bioavailable delta opioid receptor agonist for the treatment of pain ( Ki of 0.8 nM ). ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.
Product information
CAS Number: 850173-95-4
Molecular Weight: 428.95
Formula: C24H29ClN2O3
Chemical Name: N,N-diethyl-4-{5-hydroxyspiro[chromene-2,4'-piperidin]-4-yl}benzamide hydrochloride
Smiles: Cl.CCN(CC)C(=O)C1C=CC(=CC=1)C1=CC2(CCNCC2)OC2=CC=CC(O)=C12
InChiKey: ZFNLSWREIULTDO-UHFFFAOYSA-N
InChi: InChI=1S/C24H28N2O3.ClH/c1-3-26(4-2)23(28)18-10-8-17(9-11-18)19-16-24(12-14-25-15-13-24)29-21-7-5-6-20(27)22(19)21;/h5-11,16,25,27H,3-4,12-15H2,1-2H3;1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.