详情描述
AMZ30 (ML136, CS-2122) is a selective and covalent inhibitor of protein phosphatase methylesterase-1(PME-1) with IC50 of 0.60 μM. AMZ30 reduces the demethylated form of PP2A in living cells.
Product information
CAS Number: 1313613-09-0
Molecular Weight: 461.44
Formula: C19H12FN3O6S2
Chemical Name: (2E)-2-(4-fluorobenzenesulfonyl)-3-[1-(3-nitrobenzenesulfonyl)-1H-pyrrol-2-yl]prop-2-enenitrile
Smiles: N#C/C(=C\C1=CC=CN1S(=O)(=O)C1=CC(=CC=C1)[N+]([O-])=O)/S(=O)(=O)C1C=CC(F)=CC=1
InChiKey: GUCUORSUHTZMBW-YBFXNURJSA-N
InChi: InChI=1S/C19H12FN3O6S2/c20-14-6-8-17(9-7-14)30(26,27)19(13-21)11-15-4-2-10-22(15)31(28,29)18-5-1-3-16(12-18)23(24)25/h1-12H/b19-11+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.