Lorcaserin

Lorcaserin is an orally active, small-molecule 5-hydroxytryptamine 2C agonist for the potential treatment of obesity and diabetes. Lorcaserin is discontinued (DEA controlled substance).

Product information

CAS Number: 616202-92-7

Molecular Weight: 195.69

Formula: C11H14ClN

Chemical Name: (1R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Smiles: C[C@H]1CNCCC2=CC=C(Cl)C=C21

InChiKey: XTTZERNUQAFMOF-QMMMGPOBSA-N

InChi: InChI=1S/C11H14ClN/c1-8-7-13-5-4-9-2-3-10(12)6-11(8)9/h2-3,6,8,13H,4-5,7H2,1H3/t8-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Aronne L, Shanahan W, Fain R, Glicklich A, Soliman W, Li Y, Smith S. Safety and efficacy of lorcaserin: a combined analysis of the BLOOM and BLOSSOM trials. Postgrad Med. 2014 Oct;126(6):7-18.
2. Serafine KM, Rice KC, France CP. Directly Observable Behavioral Effects of Lorcaserin in Rats. J Pharmacol Exp Ther. 2015 Dec;355(3):381-5. doi: 10.1124/jpet.115.228148. Epub 2015 Sep 17.
3. Lorcaserin. In obesity: unacceptable risks. Prescrire Int. 2014 May;23(149):117-20.

Products are for research use only. Not for human use.