详情描述
Azido-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 86520-52-7
Molecular Weight: 175.19
Formula: C6H13N3O3
Chemical Name: 2-[2-(2-azidoethoxy)ethoxy]ethan-1-ol
Smiles: [N-]=[N+]=NCCOCCOCCO
InChiKey: PMNIHDBMMDOUPD-UHFFFAOYSA-N
InChi: InChI=1S/C6H13N3O3/c7-9-8-1-3-11-5-6-12-4-2-10/h10H,1-6H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (570.81 mM; Need ultrasonic) H2O : 50 mg/mL (285.40 mM; Need ultrasonic)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
Products are for research use only. Not for human use.