Azido-PEG7-amine

Azido-PEG7-amine is a non-cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG7-amine is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1333154-77-0

Molecular Weight: 394.46

Formula: C16H34N4O7

Chemical Name: 23-azido-3, 6, 9, 12, 15, 18, 21-heptaoxatricosan-1-amine

Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCN

InChiKey: VZKXLNRXAFTBOW-UHFFFAOYSA-N

InChi: InChI=1S/C16H34N4O7/c17-1-3-21-5-7-23-9-11-25-13-15-27-16-14-26-12-10-24-8-6-22-4-2-19-20-18/h1-17H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (253.51 mM; Need ultrasonic) H2O : 100 mg/mL (253.51 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Kevin W. Gillman, et al. Macrocyclic peptides useful as immunomodulators. WO2016077518A1.

Products are for research use only. Not for human use.