详情描述
AG126 is a tyrosine kinase inhibitor which can prevent the activation of mitogen-activated protein kinase p42MAPK (ERK2).
Product information
CAS Number: 118409-62-4
Molecular Weight: 215.17
Formula: C10H5N3O3
Synonym:
Tyrphostin AG126
Chemical Name: 2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedinitrile
Smiles: N#CC(=CC1=CC(O)=C(C=C1)[N+]([O-])=O)C#N
InChiKey: DUQADSPERJRQBW-UHFFFAOYSA-N
InChi: InChI=1S/C10H5N3O3/c11-5-8(6-12)3-7-1-2-9(13(15)16)10(14)4-7/h1-4,14H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (464.75 mM; Need ultrasonic and warming)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Cuzzocrea S, et al. The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation. Am J Pathol. 2000 Jul;157(1):145-58.
Products are for research use only. Not for human use.