详情描述
Duocarmycin TM is an exceptionally potent antitumor antibiotic. Duocarmycin TM is a DNA alkylator.
Product information
CAS Number: 157922-77-5
Molecular Weight: 466.91
Formula: C25H23ClN2O5
Chemical Name: (1S)-1-(chloromethyl)-3-(5, 6, 7-trimethoxy-1H-indole-2-carbonyl)-1H, 2H, 3H-benzo[e]indol-5-ol
Smiles: COC1=CC2C=C(NC=2C(OC)=C1OC)C(=O)N1C[C@@H](CCl)C2C1=CC(O)=C1C=CC=CC1=2
InChiKey: NRHDGIYFJJUFKN-CQSZACIVSA-N
InChi: InChI=1S/C25H23ClN2O5/c1-31-20-9-13-8-17(27-22(13)24(33-3)23(20)32-2)25(30)28-12-14(11-26)21-16-7-5-4-6-15(16)19(29)10-18(21)28/h4-10,14,27,29H,11-12H2,1-3H3/t14-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 50 mg/mL (107.09 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Dale L. Boger, et al. Critical Role of the Linking Amide in CC-1065 and the Duocarmycins: Implications on the Source of DNA Alkylation Catalysis. J. Am. Chem. Soc. 1998, 120, 11554-11557.
Products are for research use only. Not for human use.