MO-I-500

MO-I-500 is the first inhibitor of the RNA demethylase FTO, demonstrating anticonvulsant activity.

Product information

CAS Number: 1585219-04-0

Molecular Weight: 317.75

Formula: C12H12ClNO5S

Chemical Name: N-(3, 4-Dihydroxy-5-(4-chlorophenyl)-2-furanyl)ethanesulfonamide

Smiles: CCS(=O)(=O)NC1OC(C2C=CC(Cl)=CC=2)=C(O)C=1O

InChiKey: WWHUSZQHRUNRSB-UHFFFAOYSA-N

InChi: InChI=1S/C12H12ClNO5S/c1-2-20(17,18)14-12-10(16)9(15)11(19-12)7-3-5-8(13)6-4-7/h3-6,14-16H,2H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Singh B, Kinne HE, Milligan RD, Washburn LJ, Olsen M, Lucci A. Important Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic Challenge. PLoS One. 2016 Jul 8;11(7):e0159072. doi: 10.1371/journal.pone.0159072. PMID: 27390851; PMCID: PMC4938613.

Products are for research use only. Not for human use.