Secretin, canine

Secretin, canine is an endocrine hormone that stimulates the secretion of bicarbonate-rich pancreatic fluids. Secretin, canine can regulates gastric chief cell function and paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.

Product information

CAS Number: 110786-77-1

Molecular Weight: 3069.43

Formula: C131H222N44O41

Chemical Name: Secretin, canine

Smiles: C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC1=CN=CN1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O

InChiKey: FGZMZLCGQWXSNU-ICFIFICISA-N

InChi: InChI=1S/C131H222N44O41/c1-60(2)43-81(120(209)174-100(66(13)14)103(135)192)153-95(184)53-149-106(195)77(31-35-93(133)182)158-116(205)84(46-63(7)8)166-118(207)85(47-64(9)10)164-110(199)75(29-23-41-147-130(140)141)155-112(201)78(32-36-94(134)183)160-117(206)83(45-62(5)6)162-109(198)73(27-21-39-145-128(136)137)154-104(193)67(15)152-122(211)89(55-176)170-114(203)80(34-38-98(188)189)159-108(197)74(28-22-40-146-129(138)139)156-115(204)82(44-61(3)4)163-111(200)76(30-24-42-148-131(142)143)157-123(212)91(57-178)171-119(208)86(48-65(11)12)165-113(202)79(33-37-97(186)187)161-124(213)92(58-179)172-127(216)102(69(17)181)175-121(210)87(49-70-25-19-18-20-26-70)168-126(215)101(68(16)180)173-96(185)54-150-107(196)88(51-99(190)191)167-125(214)90(56-177)169-105(194)72(132)50-71-52-144-59-151-71/h18-20,25-26,52,59-69,72-92,100-102,176-181H,21-24,27-51,53-58,132H2,1-17H3,(H2,133,182)(H2,134,183)(H2,135,192)(H,144,151)(H,149,195)(H,150,196)(H,152,211)(H,153,184)(H,154,193)(H,155,201)(H,156,204)(H,157,212)(H,158,205)(H,159,197)(H,160,206)(H,161,213)(H,162,198)(H,163,200)(H,164,199)(H,165,202)(H,166,207)(H,167,214)(H,168,215)(H,169,194)(H,170,203)(H,171,208)(H,172,216)(H,173,185)(H,174,209)(H,175,210)(H,186,187)(H,188,189)(H,190,191)(H4,136,137,145)(H4,138,139,146)(H4,140,141,147)(H4,142,143,148)/t67-,68+,69+,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,100-,101-,102-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Wollin A, et al. Actions of histamine, secretin, and PGE2 on cyclic AMP production by isolated canine fundic mucosal cells. Am J Physiol. 1979 Nov;237(5):E437-43.

Products are for research use only. Not for human use.