Antrodin A

Antrodin A, also known as Camphorataanhydride A, is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflammatory capacity of the liver and maintaining the stability of the intestinal flora.a natural product from mycelium of Antrodia camphorata. Antrodin A alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice.

Product information

CAS Number: 656830-24-9

Molecular Weight: 314.38

Formula: C19H22O4

Synonym:

Camphorataanhydride A

656830-24-9

CHEMBL471117

SCHEMBL1971868

US9115083, Compound 1

BDBM175071

EX-A4258

3-[4-(3-methylbut-2-enoxy)phenyl]-4-(2-methylpropyl)furan-2,5-dione

3-isobutyl-4-[4-(3-methylbut-2-enoxy)phenyl]furan-2,5-dione

3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl] furan-2,5-dione

3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]furan-2,5-dione

3-Isobutyl-4-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)furan-2,5-dione

Chemical Name: 2,5-Furandione, 3-(4-((3-methyl-2-butenyl)oxy)phenyl)-4-(2-methylpropyl)-

Smiles: CC(C)=CCOC1C=CC(=CC=1)C1=C(CC(C)C)C(=O)OC1=O

InChiKey: ZXIUCXGVUOQMSH-UHFFFAOYSA-N

InChi: InChI=1S/C19H22O4/c1-12(2)9-10-22-15-7-5-14(6-8-15)17-16(11-13(3)4)18(20)23-19(17)21/h5-9,13H,10-11H2,1-4H3

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Yi ZW, Xia YJ, Liu XF, Wang GQ, Xiong ZQ, Ai LZ. Antrodin A from mycelium of Antrodia camphorata alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice. J Ethnopharmacol. 2020 May 23;254:112681. doi: 10.1016/j.jep.2020.112681. Epub 2020 Feb 19. PMID: 32087320.
2. Xie JQ, Chen YC, Sun ZH, Liu HX, Li SN, Li HH, Gao XX, Zhang WM. [Sesquiterpenoids of endophytic fungus Cerrena sp. from Pogostemon cablin and their cytotoxic activities]. Zhongguo Zhong Yao Za Zhi. 2017 May;42(9):1693-1698. Chinese. doi: 10.19540/j.cnki.cjcmm.20170224.009. PMID: 29082691.
3. He YC, Lu ZH, Shi P, Hao JC, Zhao ZJ, Xie HT, Mao P, Chen SJ. Anti-herpes simplex virus activities of bioactive extracts from Antrodia camphorata mycelia. Antivir Ther. 2016;21(5):377-83. doi: 10.3851/IMP2988. Epub 2015 Aug 27. PMID: 26313544.

Products are for research use only. Not for human use.