详情描述
Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines.
Product information
CAS Number: 147084-10-4
Molecular Weight: 307.39
Formula: C19H21N3O
Chemical Name: 2-(1-Methylpiperidin-4-ylidene)-4, 7-diazatricyclo[8.4.0.0(3, 7)]tetradeca- 1(14), 3, 5, 10, 12-pentaene-6-carbaldehyde
Smiles: CN1CCC(CC1)=C1C2=NC=C(C=O)N2CCC2=CC=CC=C12
InChiKey: MWTBKTRZPHJQLH-UHFFFAOYSA-N
InChi: InChI=1S/C19H21N3O/c1-21-9-6-15(7-10-21)18-17-5-3-2-4-14(17)8-11-22-16(13-23)12-20-19(18)22/h2-5,12-13H,6-11H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 28 mg/mL(91.08 mM). Water: Insoluble.
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Annabelle C Gallois-Bernos, et al. Journal of Receptor, Ligand and Channel Research. 2012(5):9–20.
Products are for research use only. Not for human use.