详情描述
OAC2 is an Oct4 activator used to enhance iPSC reprogramming efficiency
Product information
CAS Number: 6019-39-2
Molecular Weight: 236.27
Formula: C15H12N2O
Chemical Name: N-1H-indol-5-yl-benzamide
Smiles: O=C(NC1C=C2C=CNC2=CC=1)C1C=CC=CC=1
InChiKey: JCAFGYWSIWYMOX-UHFFFAOYSA-N
InChi: InChI=1S/C15H12N2O/c18-15(11-4-2-1-3-5-11)17-13-6-7-14-12(10-13)8-9-16-14/h1-10,16H,(H,17,18)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 47 mg/mL(198.92 mM). Water: Insoluble.
Shipping Condition: Shipped under ambien...
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Okuyama T, et al. Structural and mechanistic insights into nuclear transport and delivery of the critical pluripotency factor Oct4 to DNA. J Biomol Struct Dyn. 2017 Feb 6:1-50
- Li W, et al. Identification of Oct4-activating compounds that enhance reprogramming efficiency. Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20853-8.
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