Urolithin B

Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα. Urolithin B suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK. Urolithin B is also a regulator of skeletal muscle mass.

Product information

CAS Number: 1139-83-9

Molecular Weight: 212.20

Formula: C13H8O3

Chemical Name: 3-hydroxy-6H-benzo[c]chromen-6-one

Smiles: OC1=CC2OC(=O)C3=CC=CC=C3C=2C=C1

InChiKey: WXUQMTRHPNOXBV-UHFFFAOYSA-N

InChi: InChI=1S/C13H8O3/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)16-12(10)7-8/h1-7,14H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 42 mg/mL (197.93 mM) Ethanol 12 mg/mL (56.55 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Gyeongjin Lee, et al. Phytomedicine. 2019 Mar 1;55:50-57.
2. Julie Rodriguez, et al. J Cachexia Sarcopenia Muscle. 2017 Au

Products are for research use only. Not for human use.