ML351

ML351 is a selective inhibitor of 15-Lipoxygenase-1 (15-LOX-1 or 12/15-LOX) with IC50 of 200 nM.

Product information

CAS Number: 847163-28-4

Molecular Weight: 249.27

Formula: C15H11N3O

Chemical Name: 5-(Methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile

Smiles: CNC1OC(=NC=1C#N)C1=CC=CC2=CC=CC=C21

InChiKey: DYXYXTDIFMDJIR-UHFFFAOYSA-N

InChi: InChI=1S/C15H11N3O/c1-17-15-13(9-16)18-14(19-15)12-8-4-6-10-5-2-3-7-11(10)12/h2-8,17H,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 50 mg/mL (200.59 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Ganesha Rai, et al. Probe Reports from the NIH Molecular Libra

Products are for research use only. Not for human use.