CTPI-2

CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with KD of 3.5 μM. CTPI-2 is a unique regulator of glycolysis that limits the metabolic plasticity of cancer stem cells (CSCs).

Product information

CAS Number: 68003-38-3

Molecular Weight: 391.46

Formula: C23H25N3O3

Chemical Name: 6-(2,3-Dihydro-1,4-benzodioxin-5-yl)-N-[4-[(dimethylamino)methyl]phenyl]-2-methoxypyridin-3-amine

Smiles: COC1=NC(=CC=C1NC1=CC=C(CN(C)C)C=C1)C1=CC=CC2OCCOC=21

InChiKey: MJHHFDJNRRCUOB-UHFFFAOYSA-N

InChi: InChI=1S/C23H25N3O3/c1-26(2)15-16-7-9-17(10-8-16)24-20-12-11-19(25-23(20)27-3)18-5-4-6-21-22(18)29-14-13-28-21/h4-12,24H,13-15H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 71 mg/mL (199.02 mM) Ethanol 71 mg/mL (199.02 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Harvey R Fernandez, et al. Cell Death Differ. 2018 Jul;25(7):12

Products are for research use only. Not for human use.