GSK5182

GSK5182, 4-hydroxytamoxifen analog, is a specific inverse agonist of estrogen-related receptor γ (ERRγ) that inhibits pro-inflammatory cytokine-induced catabolic factors.

Product information

CAS Number: 877387-37-6

Molecular Weight: 417.54

Formula: C27H31NO3

Synonym:

GSK 5182

GSK-5182

Related CAS Number:

1936468-29-9 (GSK5182 (HCl))

Chemical Name: 4-[(Z)-1-[4-(2-dimethylaminoethoxy)phenyl]-5-hydroxy-2-phenylpent-1-enyl]phenol

Smiles: CN(C)CCOC1C=CC(=CC=1)/C(/C1=CC=C(O)C=C1)=C(/CCCO)\C1C=CC=CC=1

InChiKey: ZVSFNBNLNLXEFQ-RQZHXJHFSA-N

InChi: InChI=1S/C27H31NO3/c1-28(2)18-20-31-25-16-12-23(13-17-25)27(22-10-14-24(30)15-11-22)26(9-6-19-29)21-7-4-3-5-8-21/h3-5,7-8,10-17,29-30H,6,9,18-20H2,1-2H3/b27-26-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 84 mg/mL(201.17 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Yunhui Min, et al. Pharmaceuticals (Basel). 2020 Nov 27;13(12):429.

Products are for research use only. Not for human use.