ACP-105

ACP-105 is an orally available and potent selective androgen receptor modulator (SARM) with pEC50 of 9.0 and 9.4 for AR wild type and AR mutation T877A, respectively.

Product information

CAS Number: 899821-23-9

Molecular Weight: 290.79

Formula: C16H19ClN2O

Synonym:

ACP105

ACP 105

Chemical Name: 2-Chloro-4-[(1R,5R)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]-3-methylbenzonitrile

Smiles: CC1C(=CC=C(C#N)C=1Cl)N1[C@H]2CC(C)(O)C[C@H]1CC2

InChiKey: OUEODVPKPRQETQ-CHWSQXEVSA-N

InChi: InChI=1S/C16H19ClN2O/c1-10-14(6-3-11(9-18)15(10)17)19-12-4-5-13(19)8-16(2,20)7-12/h3,6,12-13,20H,4-5,7-8H2,1-2H3/t12-,13-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 58 mg/mL(199.45 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Catherine Dayger, et al. Brain Res. 2011 Mar 24;1381:134-40.
2. Nathalie Schlienger, et al. J Med Chem. 2009 Nov 26;52(22):7186-91.

Products are for research use only. Not for human use.