CBB1003 Hydrochloride

CBB1003 is a specific nonpeptide LSD1 inhibitor.

Product information

CAS Number: 2070015-02-8

Molecular Weight: 703.88

Formula: C25H36Cl5N9O4

Synonym:

CBB-1003 hydrochloride

Chemical Name: 4-({3-[4-(4-carbamimidoylbenzoyl)piperazine-1-carbonyl]-5-nitrophenyl}methyl)piperazine-1-carboximidamide pentahydrochloride

Smiles: Cl.Cl.Cl.Cl.Cl.NC(=N)C1C=CC(=CC=1)C(=O)N1CCN(CC1)C(=O)C1=CC(=CC(CN2CCN(CC2)C(N)=N)=C1)[N+]([O-])=O

InChiKey: NPEZOGXTPWOUBZ-UHFFFAOYSA-N

InChi: InChI=1S/C25H31N9O4.5ClH/c26-22(27)18-1-3-19(4-2-18)23(35)31-9-11-32(12-10-31)24(36)20-13-17(14-21(15-20)34(37)38)16-30-5-7-33(8-6-30)25(28)29;;;;;/h1-4,13-15H,5-12,16H2,(H3,26,27)(H3,28,29);5*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Hsu HC, Liu YS, Tseng KC, Yang TS, Yeh CY, You JF, Hung HY, Chen SJ, Chen HC. CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. J Cancer Res Clin Oncol. 2015 Jan;141(1):11-21.

Products are for research use only. Not for human use.