详情描述
Bindarit is a MCP-1 (Monocyte Chemotactic Protein-1) Synthesis inhibitor. Bindarit protects against bone loss induced by chikungunya virus infection. Bindarit inhibits human coronary artery smooth muscle cell proliferation, migration and phenotypic switching. Bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis. Bindarit prolongs survival and reduces renal damage in NZB/W lupus mice.
Product information
CAS Number: 130641-38-2
Molecular Weight: 324.37
Formula: C19H20N2O3
Synonym:
AF2838
AF-2838
AF 2838
Chemical Name: 2-[(1-benzyl-1H-indazol-3-yl)methoxy]-2-methylpropanoic acid
Smiles: CC(C)(OCC1=NN(CC2C=CC=CC=2)C2=CC=CC=C12)C(O)=O
InChiKey: MTHORRSSURHQPZ-UHFFFAOYSA-N
InChi: InChI=1S/C19H20N2O3/c1-19(2,18(22)23)24-13-16-15-10-6-7-11-17(15)21(20-16)12-14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3,(H,22,23)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.